Dengue Virus Net is the web resource for anyone interested in dengue. Dengue is a mosquito-borne infection that causes a severe flu-like illness (dengue fever), and sometimes a potentially lethal complication called dengue haemorrhagic fever. Global incidence of dengue has grown dramatically in recent decades. About two fifths of the world's population are now at risk. Dengue is found in tropical and sub-tropical climates worldwide, mostly in urban and semi-urban areas. Dengue is transmitted to humans by the Aedes aegypti or more rarely the Aedes albopictus mosquito, which feed during the day. Dengue haemorrhagic fever is a leading cause of serious illness and death among children in some Asian countries. A vaccine for dengue fever has been approved by the FDA in May 2019 and is commercially available in a number of countries.

The objectives of Dengue Virus Net are to be the public and professional information resource for dengue and to serve as a network in the exchange of information and news related to dengue.

• Vietnam: Dengue cases up 33% in Ho Chi Minh City - Outbreak News Today - Outbreak News Today
  Sat, 21 May 2022 20:02 GMT
• Singapore closes in on 10,000 dengue cases - Outbreak News Today - Outbreak News Today
  Fri, 20 May 2022 03:33 GMT
• Singapore reports more than 6,400 dengue cases in first four months of 2022 - Outbreak News Today - Outbreak News Today
  Tue, 03 May 2022 07:00 GMT
• PLOS Papers on Genetics of Pandemic Wellbeing, Atrial Fibrillation, Dengue Virus in Angola - GenomeWeb
  Mon, 23 May 2022 16:49 GMT
• Call to hire permanent staff ahead of dengue season - The New Indian Express
  Mon, 23 May 2022 00:11 GMT
• Presence of dengue variant puts health officials on alert - Times of India
  Sun, 22 May 2022 21:59 GMT
• Sarangani intensifies fight against dengue fever - Minda News
  Mon, 23 May 2022 14:14 GMT
• Spike in dengue cases in Mudur, Jadkal - Deccan Herald
  Sun, 22 May 2022 20:10 GMT
• Dengue virus, measles, TBI and TB disease: Are they being overlooked because of the pandemic? - Contemporary Pediatrics
  Thu, 05 May 2022 07:00 GMT
• 8 Common ​Questions About Dengue That Malaysians Should Know The Answers To - SAYS
  Mon, 23 May 2022 06:19 GMT
• Dengue spreads to 16 Antique municipalities - Panay News
  Mon, 23 May 2022 20:29 GMT
• DGHS: 15 dengue cases reported in 24 hours - Dhaka Tribune
  Mon, 23 May 2022 09:41 GMT
• Ponda sees 4 dengue cases, PMC swings into action - Times of India
  Mon, 23 May 2022 22:59 GMT
• MosBlock - The Zebra Patterned Mosquito Repellent to Combat Dengue - Branding in Asia Magazine
  Thu, 19 May 2022 23:53 GMT
• 331 dengue cases reported in Bengaluru; East Zone worst affected - Deccan Herald
  Mon, 16 May 2022 21:56 GMT

• PRO/AH/EDR> Invasive mosquito - France (03): (BT)
  Mon, 06 Sep 2021 21:28:53 -0400
  Yellow Fever, Zika virus, Dengue, Chikungunya -- France
  A potentially deadly mosquito that can carry viruses such as yellow fever and Zika has been spotted in Brittany, northern France, sparking fears they may soon land on British shores. Asian tiger mosquitoes [_Aedes albopictus_] have been confirmed to be in the commune of Domagne in the department of Ile-et-Vilaine in western Brittany.
  Health authorities are preparing an intensive campaign to rid the area of the insects with strong insecticides.
  The creatures were 1st seen in France in the

• Performance Evaluation of a Dengue IgG Rapid Diagnostic Test Designed to Determine Dengue Serostatus as Part of Prevaccination Screening Mon, 23 May 2022 06:00:00 -0400
  The World Health Organization has recommended prevaccination screening for prior dengue infection as the preferred approach prior to vaccination with the dengue vaccine CYD-TDV. These screening tests need to be highly specific and sensitive, and deliverable at the point-of-care. We evaluate here the sensitivity and specificity of the newly developed OnSite Dengue IgG rapid diagnostic test (RDT). A retrospective double-blind study of the sensitivity and specificity of the OnSite Dengue IgG RDT...
• Environmental factors influence the local establishment of Wolbachia in Aedes aegypti mosquitoes in two small communities in central Vietnam Mon, 23 May 2022 06:00:00 -0400
  Background: The wMel strain of Wolbachia has been successfully introduced into Aedes aegypti mosquitoes and subsequently shown to reduce transmission of dengue and other pathogens, under both laboratory and field conditions. Here we describe the entomological outcomes of wMel Wolbachia mosquito releases in two small communities in Nha Trang City in central Vietnam. Methods: The wMel strain of Wolbachia was backcrossed into local Aedes aegypti genotype and mosquito releases were undertaken by...
• Trojan mosquitoes control dengue Mon, 23 May 2022 06:00:00 -0400
  Dengue virus is transmitted by Aedes aegypti mosquitoes and causes the disease known as dengue. In a trial published in The New England Journal of Medicine, Utarini and colleagues report that release of wolbachia-infected A. aegypti populations in a dengue endemic area reduces the number of symptomatic cases and of hospitalisations.
• Promising Role of Emodin as Therapeutics to Against Viral Infections Mon, 23 May 2022 06:00:00 -0400
  Emodin is an anthraquinone derivative that is widely present in natural plants and has a wide spectrum of pharmacological effects, such as antibacterial, anti-inflammatory, anti-fibrotic and anticancer and so on. Through reviewing studies on antiviral effect of emodin in the past decades, we found that emodin exhibits ability of inhibiting the infection and replication of more than 10 viruses in vitro and in vivo, including herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), human...
• Effectiveness of environmental interventions to reduce entomological indices of dengue, Zika, and chikungunya vector Sun, 22 May 2022 06:00:00 -0400
  Vector-borne diseases are a major public health problem. Among them, dengue, Zika and chikungunya illnesses are increasing their incidence and geographical expansion. Since vector control is the main measure to prevent these diseases, this systematic review aims to determine the effectiveness of environmental interventions for the prevention of the transmission of these three diseases, as well as for the reduction of their burden. Experimental studies of environmental management interventions...
• Child Neurology Care in Latin America: Challenges and Potential Solutions Sun, 22 May 2022 06:00:00 -0400
  CONCLUSIONS: The virtual platforms such as Zoom, expanded during the COVID-19 pandemic, are useful not only to improve access to care through telemedicine but also for educational purposes. Collaborative efforts to support educational courses and symposia in Spanish are ongoing. It is necessary to set short- and long-term priorities to improve child neurology care in the region. Immediate priorities should focus on improving the diagnosis of neurological conditions, making emphasis on locally...
• Suppression of TGF-β/Smad2 signaling by GW788388 enhances DENV-2 clearance in macrophages Fri, 20 May 2022 06:00:00 -0400
  Dengue fever, caused by the dengue virus (DENV-1, -2, -3 and -4), affects millions of people in the tropical and subtropical regions worldwide. Severe dengue is correlated with high viraemia and cytokine storm, such as high levels of transforming growth factor-β1 (TGF-β1) in the patient's serum. Here, the TGF-β1 signaling was investigated in the context of in vitro viral clearance. Macrophages were infected with DENV-2 at MOI 5 and treated with the TGF-β receptor 1 and 2 inhibitor, GW788388....
• Ultrasound-assisted nanoemulsion of Trachyspermum ammi essential oil and its constituent thymol on toxicity and biochemical aspect of Aedes aegypti Fri, 20 May 2022 06:00:00 -0400
  Aedes aegypti is the main vector of yellow fever, chikungunya, Zika, and dengue worldwide and is managed by using chemical insecticides. Though effective, their indiscriminate use brings in associated problems on safety to non-target and the environment. This supports the use of plant-based essential oil (EO) formulations as they are safe to use with limited effect on non-target organisms. Quick volatility and degradation of EO are a hurdle in its use; the present study attempts to develop...
• Economic burden of dengue fever in China: A retrospective research study Fri, 20 May 2022 06:00:00 -0400
  CONCLUSION: The economic burden of dengue fever patients is relatively high, and medical insurance coverage should be increased to lighten patients' direct medical economic burden. At the same time, the results suggests that China should increase funding for primary health service institutions to prevent dengue fever transmission.
• Detection of pyrethroid resistance mutations and intron variants in the voltage-gated sodium channel of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus mosquitoes from Lao People's Democratic Republic Fri, 20 May 2022 06:00:00 -0400
  In Lao People's Democratic Republic, Aedes aegypti (Linnaeus 1762) and Aedes albopictus (Skuse 1894) mosquitoes (Diptera: Culicidae) are vectors of arboviral diseases such as dengue. As the treatment for these diseases is limited, control of the vectors with the use of pyrethroid insecticides is still essential. However, mutations in the voltage-gated sodium channel (vgsc) gene giving rise to pyrethroid resistance are threatening vector control programs. Here, we analysed both Ae. aegypti and...