- Knowledge, attitude and practice (KAP) and risk factors on dengue fever among children in Brazil, Fortaleza: A cross-sectional study Mon, 25 Sep 2023 06:00:00 -0400
CONCLUSIONS/SIGNIFICANCE: Our results provide insight into the prevalence of dengue seropositivity in Fortaleza, Brazil in children, and certain demographic and socioeconomic characteristics associated with children's risk of being seropositive. They also suggest that KAP may not identify those more at-risk for dengue, although understanding and enhancing households' KAP is crucial for effective community dengue control and prevention initiatives.
- Computer-aided identification of dengue virus NS2B/NS3 protease inhibitors: an integrated molecular modelling approach for screening of phytochemicals Mon, 25 Sep 2023 06:00:00 -0400
Globally, dengue (DENV) fever has appeared as the most widespread vector-borne disease, affecting more than 100 million individuals annually. No approved anti-DENV therapy or preventive vaccine is available yet. DENV NS3 protein is associated with protease activity and is essential for viral replication process within the host cell. NS2B is linked with NS3 protein as a cofactor. Hence, NS3/NS2B is a potential druggable target for developing inhibitors against dengue virus. In the present study,...
- Once Forgotten Now Re-emerging: Scrub Typhus Infection in Pediatric Patients From North West India Mon, 25 Sep 2023 06:00:00 -0400
Background Scrub typhus is an important cause of acute febrile illness in children. It is one of the re-emerging infections in the Asia Pacific region. It is caused by the gram-negative bacteria Orientia tsutsugamushi and is spread by the bite of trombiculid mites. The initial symptomatology is nonspecific with fever, headache, vomiting, etc. The presence of eschar is said to be pathognomic. It is a systemic illness, and vasculitis is the basic pathogenic mechanism. Materials and methods A...
- Falciparum Malaria, Leptospirosis, and Vibrio mimicus Encephalitis in a Resilient Patient: A Remarkable Case of Triple Infection Survival Mon, 25 Sep 2023 06:00:00 -0400
Malaria is referred to as a "rainy season disease" and is brought on by Plasmodium species. Leptospira interrogans, a spirochete, cause zoonosis leptospirosis. It is pretty uncommon for both diseases to coinfect one another. Before assuming a fever is caused by a vector-borne disease, it is essential to first rule out other possible causes, regardless of the patient's risk factors. This case report demonstrates an unusual coinfection and how it manifests. The patient can avoid many deadly...
- Genome evolution of dengue virus serotype 1 under selection by Wolbachia pipientis in Aedes aegypti mosquitoes Mon, 25 Sep 2023 06:00:00 -0400
The introgression of antiviral strains of Wolbachia into Aedes aegypti mosquito populations is a public health intervention for the control of dengue. Plausibly, dengue virus (DENV) could evolve to bypass the antiviral effects of Wolbachia and undermine this approach. Here, we established a serial-passage system to investigate the evolution of DENV in Ae. aegypti mosquitoes infected with the wMel strain of Wolbachia. Using this system, we report on virus genetic outcomes after twenty passages of...
- Daily dataset of precipitation and temperature in the Department of Cauca, Colombia Mon, 25 Sep 2023 06:00:00 -0400
This study used the geostatistical Kriging methodology to reduce the spatial scale of a host of daily meteorological variables in the Department of Cauca (Colombia), namely, total precipitation and maximum, minimum, and average temperature. The objective was to supply a high-resolution database from 01/01/2015 to 31/12/2021 in order to support the climate component in a project led by the National Institute of Health (INS) named "Spatial Stratification of dengue based on the identification of...
- Seroprevalence of dengue virus infection in Pune City in India, 2019: A decadal change Sun, 24 Sep 2023 06:00:00 -0400
CONCLUSIONS: There was a significant increase in the intensity of dengue virus transmission in Pune City over the decade. Since over 85% of the participants above nine years of age had exposure to DENV by 2019, dengue vaccine introduction can be considered. Moreover, such repeated serosurveys in different regions might inform about the readiness of the population for dengue vaccination.
- Dengue vaccine acceptance and willingness to pay: a systematic review and meta-analysis Sat, 23 Sep 2023 06:00:00 -0400
CONCLUSIONS: We were able to obtain global estimates of vaccine acceptance and willingness to pay and identify the associated factors that influence these values. This knowledge is relevant for the planning of future vaccination strategies.
- Insecticide susceptibility status on Aedes aegypti (Linn) and Aedes albopictus (Skuse) of Chittorgarh district, Rajasthan, India Fri, 22 Sep 2023 06:00:00 -0400
Vector-borne diseases are a major burden to human health. It accounts for more than 17% of the total infectious diseases and causes more than 0.7 million deaths annually. Mosquitoes are potential vectors for many vector-borne diseases that cause illness to public health, globally. Vector species of the genus Aedes i.e., Aedes aegypti and Aedes albopictus are the vector for many arboviruses such as dengue, chikungunya, yellow fever, and Zika in India. Dengue is one of the most prevalent viral...
- Myocarditis manifestations in dengue cases: A systematic review and meta-analysis Fri, 22 Sep 2023 06:00:00 -0400
CONCLUSION: Myocarditis in dengue patients is a significant and understudied complication in many aspects. To prevent dengue-associated myocarditis, appropriate measures such as early detection of cases and signs, symptoms-based diagnosis via electrocardiography and echocardiography, as well as relevant vector control policies must be implemented.